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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASGRP3 All Species: 39.7
Human Site: S172 Identified Species: 97.04
UniProt: Q8IV61 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV61 NP_001132960.1 690 78332 S172 H K S F R R I S F T D Y Q S Y
Chimpanzee Pan troglodytes XP_525730 690 78366 S172 H K S F R R I S F T D Y Q S Y
Rhesus Macaque Macaca mulatta XP_001106737 690 78344 S172 H K S F R R I S F T D Y Q S Y
Dog Lupus familis XP_854079 697 78861 S172 H K S F R R I S F T D Y Q S Y
Cat Felis silvestris
Mouse Mus musculus Q9Z1S3 795 90285 S225 F K S F R R I S F S D Y Q N Y
Rat Rattus norvegicus Q9R1K8 795 90226 S225 F K S F R R I S F S D Y Q N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511025 724 82163 S181 H K S F R R I S F T D Y Q S Y
Chicken Gallus gallus NP_001006401 691 78529 S172 H K S F R R I S F T D Y Q S Y
Frog Xenopus laevis Q6NTL4 791 90153 S221 F K A F R R I S F S D Y Q N Y
Zebra Danio Brachydanio rerio NP_001103934 708 80321 S172 Y K S I R R I S F T D Y Q S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.4 95.4 N.A. 47.4 47.4 N.A. 82.1 86.8 48.6 72.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.7 97.1 N.A. 63.1 63.4 N.A. 87 91.7 63.8 81.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 100 100 73.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 30 0 0 90 0 0 0 0 100 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 100 0 0 0 0 0 0 0 0 % I
% Lys: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % Q
% Arg: 0 0 0 0 100 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 90 0 0 0 0 100 0 30 0 0 0 70 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 100 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _